Epigenetic Mechanisms of Depression and Antidepressant Action
نویسندگان
چکیده
منابع مشابه
Epigenetic alterations in depression and antidepressant treatment
Epigenetic modifications control chromatin structure and function, and thus mediate changes in gene expression, ultimately influencing protein levels. Recent research indicates that environmental events can induce epigenetic changes and, by this, contribute to long-term changes in neural circuits and endocrine systems associated with altered risk for stress-related psychiatric disorders such as...
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می توان گفت واقعیت چند لایه ا ی کلاس های زبان انگلیسی بسیار حائز اهمیت است، زیرا عواطف و بینش های زبان آموزان تحت تاثیر قرار می گیرد. در پژوهش پیش رو، گفته می شود که دبیران با در پیش گرفتن رویکرد فرا-انسانگرایی ، قادرند در زندگی دانش آموزانشان نقش مهمی را ایفا سازند. بر اساس گفته ی ویلیامز و بردن (2000)، برای کرل راجرز، یکی از بنیان گذاران رویکرد انسانگرایی ، یادگیری بر مبنای تجربه، نوعی از یاد...
Involvement of prolactin and somatostatin in depression and the mechanism of action of antidepressant drugs.
Neuropeptides have been implicated in the physiology and pathophysiology of stress responses and therefore may play an important role in the pathogenesis of affective disorders such as Major Depression Disorder (MDD). The data presented in this mini-review demonstrate the role of prolactin (PRL) and somatostatin (STT) in the pathology and pharmacotherapy of MDD, focusing particularly on the res...
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Depression is one of the most frequent and severe mental disorder. Since the discovery of antidepressant (AD) properties of the imipramine and then after of other tricyclic compounds, several classes of psychotropic drugs have shown be effective in treating major depressive disorder (MDD). However, there is a wide range of variability in response to ADs that might lead to non response or partia...
متن کامل[Trazodon--the antidepressant: mechanism of action and its position in the treatment of depression].
The pharmacological properties and possible clinical use of trazodon in the treatment of depression are presented. Trazodon is the only antidepressant from the SARI (Serotonin Antagonists and Reuptake Inhibitors) group available in Poland. It has a wide pharmacodynamic profile (being an antagonist of 5-HT2A and 5-HT2C serotoninergic receptors, alpha1 and alpha2 adrenergic receptors as well as H...
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ژورنال
عنوان ژورنال: Annual Review of Pharmacology and Toxicology
سال: 2013
ISSN: 0362-1642,1545-4304
DOI: 10.1146/annurev-pharmtox-010611-134540